Vidarabine

• CAS: 5536-17-4
• Catalog Number: ACM5536174
• Category: Inhibitors
• Molecular Weight: 267.24
• Molecular Formula: C₁₀H₁₃N₅O₄
• Description: Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses. Vidarabine has IC50s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2. Vidarabine also has anti-orthopoxvirus activity.
• Synonyms: ARABINOSYL-ADENINE;6-AMINO-9-BETA-D-ARABINOFURANOSYLPURINE;ADENINE-BETA-D-ARABINOFURANOSIDE;ADENINE-9-BETA-D-ARABINOFURANOSIDE;9-BETA-D-ARABINOSYLADENINE;9-BETA-D-ARABINOFURANOSYLADENINE;2-ARAADENOSINE;SPONGOADENOSINE
• Melting Point: 260-265°C (dec.)
• Hazard Statements: Xn,Xi
• Safety Description: 36/37-36-26
• Supplemental Hazard Statements: H361
• Symbol: GHS08

Custom Q&A

What is the molecular formula of Vidarabine?

The molecular formula of Vidarabine is C10H13N5O4.

What are some synonyms for Vidarabine?

Some synonyms for Vidarabine include Adenine arabinoside, Ara-A, and Vira-A among others.

What is the molecular weight of Vidarabine?

The molecular weight of Vidarabine is 267.24 g/mol.

What is the IUPAC name of Vidarabine?

The IUPAC name of Vidarabine is (2R,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol.

What is the InChIKey of Vidarabine?

The InChIKey of Vidarabine is OIRDTQYFTABQOQ-UHTZMRCNSA-N.

What is the canonical SMILES of Vidarabine?

The canonical SMILES of Vidarabine is C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N.

What is the CAS number of Vidarabine?

The CAS number of Vidarabine is 5536-17-4.

What is the European Community (EC) Number of Vidarabine?

The European Community (EC) Number of Vidarabine is 226-893-9.

What is the KEGG ID of Vidarabine?

The KEGG ID of Vidarabine is D06298.

What is the XLogP3 value of Vidarabine?

The XLogP3 value of Vidarabine is -1.1.

Synthetic Use

Upstream Synthesis Route 1

• 65174-95-0

• 5536-17-4

Reference: [1] Patent: CN107556356, 2018, A, . Location in patent: Paragraph 0019; 0020

Upstream Synthesis Route 2

• 3257-73-6

• 5536-17-4

Reference: [1] Synthesis, 1981, # 5, p. 396 - 397
[2] Organic and Biomolecular Chemistry, 2005, vol. 3, # 3, p. 462 - 470

Upstream Synthesis Route 3

• 3083-77-0
• 66224-66-6

• 5536-17-4

Reference: [1] Agricultural and Biological Chemistry, 1985, vol. 49, # 7, p. 2167 - 2171

Upstream Synthesis Route 4

• 69304-45-6

• 5536-17-4

Reference: [1]Tetrahedron,1984,vol. 40,p. 125 - 135
[2]Chemical and Pharmaceutical Bulletin,1983,vol. 31,p. 1582 - 1592

Upstream Synthesis Route 5

• 3083-77-0
• 66224-66-6

• 5536-17-4

Reference: [1]Agricultural and Biological Chemistry,1985,vol. 49,p. 2167 - 2171

Downstream Synthesis Route 1

• 69304-37-6
• 5536-17-4

• 87792-02-7

Reference: [1]Nucleosides and Nucleotides,1999,vol. 18,p. 137 - 151

* For details of the synthesis route, please refer to the original source to ensure accuracy.