TMX-4100

• CAS: 2367619-63-2
• Catalog Number: ACM-MG-2367619632
• Category: Molecular Glues
• Molecular Weight: 262.29
• Molecular Formula: C11H10N4O2S
• Description: TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader. TMX-4100 shows a high degradation preference for PDE6D with the DC50 values less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4100 can be used for the research of multiple myeloma.
• IUPAC Name: 3-(4-thiophen-3-yltriazol-1-yl)piperidine-2,6-dione
• SMILES: O=C(C(N1N=NC(C2=CSC=C2)=C1)CC3)NC3=O
• InChI: InChI=1S/C11H10N4O2S/c16-10-2-1-9(11(17)12-10)15-5-8(13-14-15)7-3-4-18-6-7/h3-6,9H,1-2H2,(H,12,16,17)
• InChI Key: PGEUBQZQGXWTFO-UHFFFAOYSA-N
• Appearance: White to off-white solid
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Store at 4 °C