TCIP3

• CAS: 3067681-36-8
• Catalog Number: ACM-MG-3067681368
• Category: Molecular Glues
• Molecular Weight: 1177.74
• Molecular Formula: C58H71ClF2N16O7
• Description: TCIP3 is a bivalent molecular glue with with dual binding to p300/CBP and BCL6. TCIP3 redirects p300 and CBP to activate programmed cell death genes normally repressed by the oncogenic driver, BCL6. TCIP3 can be used for the study of diffuse large B cell lymphomas (DLBCLs). TCIP3 exhibits no toxicity in non-transformed tonsillar lymphocytes or fibroblasts.
• SMILES: O=C(N1CC2=C(CC1)N(C3CCN(CC3)C(CCN4CCN(CC4)C(C5CCN(CC5)C6=NC=C(C(NC7=CC(C=C(C(N8C)=O)OCC(NC)=O)=C8C(OC)=C7)=N6)Cl)=O)=O)N=C2N9C%10=C(CCC9)C=C(C%11=CN(C)N=C%11)C(C(F)F)=C%10)NC
• Appearance: White to off-white solid
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: 4 °C, protect from light