CAS
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TBK1 degrader-4
Catalog Number
ACM-MG-00048
Category
Molecular Glues
Molecular Weight
732.91
Molecular Formula
C42H52N8O4
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- Product Description
- Case Study
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Specification
Description
TBK1 degrader-4 (Compound 30) is a molecular glue degrader targeting TBK1. TBK1 degrader-4 effectively inhibits cyst growth, alleviates inflammation, and reduces the levels of pro-inflammatory factors such as Ccl2, IFNβ, and IL-6. TBK1 degrader-4 is promising for research of autosomal dominant polycystic kidney disease (ADPKD).
SMILES
O=C(N1CCN(CC2CCN(CC3=CC(NC4=NC=C(C=CN5CCCNC(C6CCC6)=O)C5=N4)=CC=C3)CC2)CC1)/C=C/C(C7=CC=C(OC)C=C7)=O
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Please store the product under the recommended conditions.
Please kindly note that our products are for research use only.
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