Product Name
Sodium Oleate
Category
Soaps of Fatty Acids
Description
Bretazenil (Ro16-6028) is an imidazopyrrolobenzodiazepine anxiolytic drug that is derived from the benzodiazepine family and was invented in 1988. It is most closely related in structure to the benzodiazepine antagonist flumazenil, although its effects are somewhat different. It is classed as a high-potency benzodiazepine due to its high-affinity binding to benzodiazepine binding sites where it acts as a partial agonist. Its profile as a partial agonist and preclinical trial data suggests that it may have a reduced adverse effect profile. In particular, bretazenil has been proposed to cause a less strong development of tolerance and withdrawal syndrome. Bretazenil differs from traditional 1,4-benzodiazepines by being a partial agonist and because it binds to α1, α2, α3, α4, α5, and α6 subunit-containing GABAA receptor benzodiazepine receptor complexes. 1,4-benzodiazepines bind only to α1, α2, α3 and α5 GABAA benzodiazepine receptor complexes.
IUPAC Name
Sodium;(Z)-octadec-9-enoate
Molecular Formula
232-235 °C(lit.)
Canonical SMILES
CCCCCCCCC=CCCCCCCCC(=O)[O-].[Na+]
InChI
InChI=1S/C18H34O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h9-10H,2-8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b10-9-;
InChI Key
BCKXLBQYZLBQEK-KVVVOXFISA-M
Boiling Point
359.999 °C/760 mmHg
Melting Point
232-235 °C(lit.)
Appearance
White to slightly yellow powder
Isomeric SMILES
CCCCCCCC/C=C\CCCCCCCC(=O)[O-].[Na+]
Monoisotopic Mass
304.23782457
Sodium Derivative Of
Oleate
Stability
Stable. Incompatible with strong oxidizing agents.
Topological Polar Surface Area
40.1 Ų
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