Structure

SJPYT-195

CAS
2973762-16-0
Catalog Number
ACM-MG-2973762160
Category
Molecular Glues
Molecular Weight
666.68
Molecular Formula
C35H34N6O8

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Specification

Description
SJPYT-195 is a cytotoxic GSPT1 degrader and can be used for PROTAC synthesis.
IUPAC Name
N-[3-tert-butyl-5-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyphenyl]-1-(2,5-dimethoxyphenyl)-5-methyltriazole-4-carboxamide
SMILES
O=C(C1=C(C)N(C2=CC(OC)=CC=C2OC)N=N1)NC3=CC(OC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=CC(C(C)(C)C)=C3
InChI
InChI=1S/C35H34N6O8/c1-18-30(38-39-41(18)25-17-21(47-5)10-12-26(25)48-6)32(44)36-20-14-19(35(2,3)4)15-22(16-20)49-27-9-7-8-23-29(27)34(46)40(33(23)45)24-11-13-28(42)37-31(24)43/h7-10,12,14-17,24H,11,13H2,1-6H3,(H,36,44)(H,37,42,43)
InChI Key
YYDMLWLLMFAABT-UHFFFAOYSA-N
Appearance
White to off-white solid
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Store at 4 °C

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