Sematilide hydrochloride

• CAS: 101526-62-9
• Catalog Number: ACM101526629-1
• Category: Others
• Molecular Weight: 349.87
• Molecular Formula: C14H24ClN3O3S
• Description: Sematilide, also known as CK-1752, is a class III antiarrhythmic. It is a selective delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of action potential duration and refractoriness.
• Synonyms: Sematilide hydrochloride; Sematilide HCl; Sematilide hydrochloride; Sematilide; CK-1752A; CK1752A; CK 1752A; CK-1752; CK1752; CK 1752
• IUPAC Name: Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monohydrochloride
• Canonical SMILES: O=C(NCCN(CC)CC)C1=CC=C(NS(=O)(C)=O)C=C1.[H]Cl
• InChI: InChI=1S/C14H23N3O3S.ClH/c1-4-17(5-2)11-10-15-14(18)12-6-8-13(9-7-12)16-21(3,19)20;/h6-9,16H,4-5,10-11H2,1-3H3,(H,15,18);1H
• InChI Key: OKXAJGDKHKNFAX-UHFFFAOYSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 101526-83-4 (free base); 101526-62-9 (HCl)
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 48.06; H, 6.91; Cl, 10.13; N, 12.01; O, 13.72; S, 9.16
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).