Structure

(S,S)-PLX-4545

CAS
2892065-49-3
Catalog Number
ACM-MG-2892065493
Category
Molecular Glues
Molecular Weight
473.56
Molecular Formula
C28H31N3O4

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Specification

Description
(S,S)-PLX-4545 (Compound I) is an orally active and cereblon-based molecular glue degrader of IKZF2 (zinc finger transcription factor Helios). (S,S)-PLX-4545 can be used for the study of IKZF2-mediated diseases or disorders, such as proliferative diseases or disorders and/or cancer.
SMILES
O=C1CCC(C(N1)=O)N2CC3=C(C2=O)C=CC(O[C@H]4CCCC[C@@H]4N5CC(C5)C6=CC=CC=C6)=C3
Appearance
Solid
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Store at -20 °C

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