CAS
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QXG-6442
Catalog Number
ACM-MG-00044
Category
Molecular Glues
Molecular Weight
403.39
Molecular Formula
C21H17N5O4
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Specification
Description
QXG-6442 is a CK1α Molecular Glue Degrader. QXG-6442 exhibits CK1α degradation potency with a DC50 of 5.7 nM and a Dmax of 90%. QXG-6442 induces antiproliferative effects in MOLM-14 cell line.
SMILES
O=C(C1=CN2C=CC=CC2=N1)NC3=CC4=C(C(N(C4)C5CCC(NC5=O)=O)=O)C=C3
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Please store the product under the recommended conditions.
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