PT-179

• CAS: 2924858-25-1
• Catalog Number: ACM-MG-2924858251
• Category: Molecular Glues
• Molecular Weight: 343.33
• Molecular Formula: C17H17N3O5
• Description: PT-179 is able to specifically bind CRBN, form a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediate the degradation of the tagged protein.
• IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-5-morpholin-4-ylisoindole-1,3-dione
• SMILES: O=C1C2=CC=C(N3CCOCC3)C=C2C(N1C4C(NC(CC4)=O)=O)=O
• InChI: InChI=1S/C17H17N3O5/c21-14-4-3-13(15(22)18-14)20-16(23)11-2-1-10(9-12(11)17(20)24)19-5-7-25-8-6-19/h1-2,9,13H,3-8H2,(H,18,21,22)
• InChI Key: CCCSRHUSXCBFJZ-UHFFFAOYSA-N
• Appearance: Light yellow to yellow solid
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Store at 4 °C