PROTAC GSPT1 degrader-2

• CAS: 3024909-61-0
• Catalog Number: ACM-MG-3024909610
• Category: Molecular Glues
• Molecular Weight: 708.21
• Molecular Formula: C38H38ClN7O5
• Description: PROTAC GSPT1 degrader-2 (compound A) is a GSPT1 molecule glue with more than 95% degradation. GSPT1 degrader-8 inhibits cell viability in HL-60 cells with an IC50 of 10 nM.
• SMILES: O=C1NC(C(CC1)N2C(C3=CC=C(N4CCC(CC4)CN5C(N(CCC5)C6=CC(C7=C(Cl)C8=C(NC=C8CC)N=C7)=CC=C6)=O)C=C3C2=O)=O)=O
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.