Structure

Pomalidomide-d5

CAS
1377838-49-7
Catalog Number
ACM-MG-1377838497
Category
Molecular Glues
Molecular Weight
278.27
Molecular Formula
C13H6D5N3O4

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Specification

Description
Pomalidomide-d5 is deuterium labeled Pomalidomide. Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors.
Synonyms
CC-4047-d5
IUPAC Name
4-amino-2-(3,4,4,5,5-pentadeuterio-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
SMILES
NC1=C2C(C(N(C2=O)C3(C(NC(C([2H])(C3([2H])[2H])[2H])=O)=O)[2H])=O)=CC=C1
InChI
InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)/i4D2,5D2,8D
InChI Key
UVSMNLNDYGZFPF-XHNMXOBISA-N
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.

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