Structure

Pomalidomide-d3

CAS
2093128-28-8
Catalog Number
ACM-MG-2093128288
Category
Molecular Glues
Molecular Weight
276.26
Molecular Formula
C13H8D3N3O4

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Specification

Description
Pomalidomide-d3 is the deuterium labeled Pomalidomide. Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors.
Synonyms
CC-4047-d3
IUPAC Name
4-amino-5,6,7-trideuterio-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
SMILES
O=C1N(C2C(NC(CC2)=O)=O)C(C3=C(N)C([2H])=C([2H])C([2H])=C31)=O
InChI
InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)/i1D,2D,3D
InChI Key
UVSMNLNDYGZFPF-CBYSEHNBSA-N
Appearance
Light yellow to yellow soild
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Store at 4 °C

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