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Structure

Perfluoro-1-iodohexane

CAS
355-43-1
Catalog Number
ACM355431
Category
Other Products
Molecular Weight
445.95
Molecular Formula
C6F13I

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Specification

Description
Bretazenil (Ro16-6028) is an imidazopyrrolobenzodiazepine anxiolytic drug that is derived from the benzodiazepine family and was invented in 1988. It is most closely related in structure to the benzodiazepine antagonist flumazenil, although its effects are somewhat different. It is classed as a high-potency benzodiazepine due to its high-affinity binding to benzodiazepine binding sites where it acts as a partial agonist. Its profile as a partial agonist and preclinical trial data suggests that it may have a reduced adverse effect profile. In particular, bretazenil has been proposed to cause a less strong development of tolerance and withdrawal syndrome. Bretazenil differs from traditional 1,4-benzodiazepines by being a partial agonist and because it binds to α1, α2, α3, α4, α5, and α6 subunit-containing GABAA receptor benzodiazepine receptor complexes. 1,4-benzodiazepines bind only to α1, α2, α3 and α5 GABAA benzodiazepine receptor complexes.
Synonyms
Tridecafluoro-1-iodohexane;PERFLUORO-N-HEXYL IODIDE;1-Iodotridecafluorohexane;Perfluorohexyl iodide;1-iodo-tridecafluoro-hexane
Melting Point
-45ºC
Flash Point
45ºC
Density
2.063
Appearance
Liquid
Hazard Codes
Xi
HS Code
29034700
LogP
5.11770
MDL Number
MFCD00001063
Refractive Index
1.3275-1.3295
RIDADR
UN 2810
Stability
Stable.
Storage Conditions
Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container. Dark room.
WGK Germany
3
Alfa Chemistry

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