Pan-RAS-IN-5

• Catalog Number: ACM-MG-00041
• Category: Molecular Glues
• Molecular Weight: 823.06
• Molecular Formula: C45H58N8O5S
• Description: Pan-RAS-IN-5 (compound 7A) is a molecular glues that can form a ternary complex with the proteins cyclophilin A (CYPA) and RAS (ON). The formation of the ternary complex can block the binding of RAS downstream of RAF and has anti-tumor effects.
• SMILES: O=C([C@@H](NC([C@H]1C[C@@H]1C)=O)CC2=NC(C3=CC(C(CC(C)(COC4=O)C)=[C@@]([C@@]5=C([C@@H](OC)C)N=CC(N6CCN(C)CC6)=C5)N7CC)=C7C=C3)=CS2)N8N[C@H]4C9CC8C9
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.