Neriifolin

• CAS: 466-07-9
• Catalog Number: ACM466079
• Category: Inhibitors
• Molecular Weight: 534.68
• Molecular Formula: C30H46O8
• Description: Neriifolin, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na+, K+-ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells[2.
• Canonical SMILES: O[C@@]12[C@@]3([H])[C@@](CC[C@@]1([C@](C4=CC(OC4)=O)([H])CC2)C)([H])[C@@]5([C@](C[C@H](CC5)O[C@H]6[C@H]([C@@H]([C@H]([C@@H](O6)C)O)OC)O)([H])CC3)C
• Appearance: Solid
• Storage: Powder-20°C, 3 years; In solvent-80°C. 6 months; -20°C, 1 month.
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: PlantsApocynaceaeCerbera manghas Linn.