Naphthol AS-E

• CAS: 92-78-4
• Catalog Number: ACM92784
• Category: Inhibitors
• Molecular Weight: 297.74
• Molecular Formula: C₁₇H₁₂ClNO₂
• Description: Naphthol AS-E is a potent and cell-permeable inhibitor of KIX-KID interaction. Naphthol AS-E directly binds to the KIX domain of CBP (Kd:8.6 µM), blocks the interaction between the KIX domain and the KID domain of CREB with IC50 of 2.26 µM. Naphthol AS-E can be used for cancer research.
• Synonyms: NAPHTHOL AS-E;NAPTHOL AS-E;N-(4-CHLOROPHENYL)-3-HYDROXY-2-NAPHTHAMIDE;c.i. azoic coupling component 10;AZOIC COUPLING COMPONENT 10;4'-CHLORO-3-HYDROXY-2-NAPHTHANILIDE;AcnaNaphtholPC;DaitoGrounderE
• IUPAC Name: N-(4-chlorophenyl)-3-hydroxynaphthalene-2-carboxamide
• InChI Key: OHAXNCGNVGGWSO-UHFFFAOYSA-N
• Boiling Point: 416.5ºC at 760 mmHg
• Melting Point: 255ºC
• Flash Point: 205.7ºC
• Density: 1.399 g/cm³
• Appearance: off-white powder
• Exact Mass: 297.05600
• Hazard Statements: Xn
• H-Bond Acceptor: 2
• H-Bond Donor: 2
• Safety Description: S7:Keep container tightly closed .; S36:Wear suitable protective clothing .; S24/25:Avoid contact with skin and eyes .
• WGK Germany: 3

Custom Q&A

What is the molecular formula of Naphthol AS-E?

The molecular formula of Naphthol AS-E is C17H12ClNO2.

What is the molecular weight of Naphthol AS-E?

The molecular weight of Naphthol AS-E is 297.7 g/mol.

What is the IUPAC name of Naphthol AS-E?

The IUPAC name of Naphthol AS-E is N-(4-chlorophenyl)-3-hydroxynaphthalene-2-carboxamide.

What is the InChI of Naphthol AS-E?

The InChI of Naphthol AS-E is InChI=1S/C17H12ClNO2/c18-13-5-7-14(8-6-13)19-17(21)15-9-11-3-1-2-4-12(11)10-16(15)20/h1-10,20H,(H,19,21).

What is the InChIKey of Naphthol AS-E?

The InChIKey of Naphthol AS-E is OHAXNCGNVGGWSO-UHFFFAOYSA-N.

What is the canonical SMILES of Naphthol AS-E?

The canonical SMILES of Naphthol AS-E is C1=CC=C2C=C(C(=CC2=C1)C(=O)NC3=CC=C(C=C3)Cl)O.

What is the CAS number of Naphthol AS-E?

The CAS number of Naphthol AS-E is 92-78-4.

What is the European Community (EC) number of Naphthol AS-E?

The European Community (EC) number of Naphthol AS-E is 202-189-7.

What is the UNII of Naphthol AS-E?

The UNII of Naphthol AS-E is 8V561WAE43.

What is the ChEMBL ID of Naphthol AS-E?

The ChEMBL ID of Naphthol AS-E is CHEMBL65653.

What is the InChI code of Naphthol AS-E?

The InChI code of Naphthol AS-E is InChI=1S/C17H12ClNO2/c18-13-5-7-14(8-6-13)19-17(21)15-9-11-3-1-2-4-12(11)10-16(15)20/h1-10,20H,(H,19,21).

What is the topological polar surface area of Naphthol AS-E?

The topological polar surface area of Naphthol AS-E is 49.3?2.