Specification
Description
N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides.
IUPAC Name
1-ethylpyrrole-2,5-dione
Canonical SMILES
CCN1C(=O)C=CC1=O
InChI Key
HDFGOPSGAURCEO-UHFFFAOYSA-N
Solubility
Soluble in water.
Appearance
White Powder to Crystal
Condition To Avoid
Light Sensitive,Air Sensitive,Heat Sensitive
Hazard Statements
T+:Verytoxic;
Safety Description
S26-S28-S36/37/39-S45
Shipping
Can be shipped at room temperature, where not in use may vary.
Stability
Stable. Combustible. Incompatible with strong oxidizing agents. Refrigerate.