Methyl 5-chloropyrazine-2-carboxylate

• CAS: 33332-25-1
• Catalog Number: ACM33332251
• Category: Other Products
• Molecular Weight: 172.57
• Molecular Formula: C₆H₅N₂O₂Cl

Synthetic Use

Upstream Synthesis Route 1

• 6164-79-0

• 27825-21-4
• 33332-25-1

Reference: [1] Magnetic Resonance in Chemistry, 2009, vol. 47, # 7, p. 617 - 624

Upstream Synthesis Route 2

• 770-00-3

• 27825-21-4
• 23611-75-8
• 33332-25-1

Reference: [1] Journal of Heterocyclic Chemistry, 1994, vol. 31, # 5, p. 1177 - 1180
[2] Journal of Chemical Research, Miniprint, 1984, # 10, p. 2860 - 2875
[3] Journal of Heterocyclic Chemistry, 1994, vol. 31, # 5, p. 1177 - 1180
[4] Journal of Heterocyclic Chemistry, 1994, vol. 31, # 5, p. 1177 - 1180

Upstream Synthesis Route 3

• 770-00-3

• 27825-21-4
• 23611-75-8
• 33332-25-1

Reference: [1]Journal of Heterocyclic Chemistry,1994,vol. 31,p. 1177 - 1180
[2]Journal of Chemical Research, Miniprint,1984,p. 2860 - 2875
[3]Journal of Heterocyclic Chemistry,1994,vol. 31,p. 1177 - 1180
[4]Journal of Heterocyclic Chemistry,1994,vol. 31,p. 1177 - 1180

Upstream Synthesis Route 4

• 13924-95-3

• 33332-25-1

Reference: [1]Patent: EP2239253,2010,A1 .Location in patent: Page/Page column 96

Downstream Synthesis Route 1

• 33332-25-1

• 13924-94-2

Reference: [1] European Journal of Pharmaceutical Sciences, 2018, vol. 124, p. 165 - 181
[2] Tetrahedron Letters, 2013, vol. 54, # 5, p. 414 - 418
[3] ACS Medicinal Chemistry Letters, 2013, vol. 4, # 4, p. 414 - 418

Downstream Synthesis Route 2

• 110-91-8
• 33332-25-1

• 1017604-09-9

Reference: [1]Current Patent Assignee: ANIMA BIOTECH - WO2021/252555, 2021, A1
Location in patent: Paragraph 00299

* For details of the synthesis route, please refer to the original source to ensure accuracy.