Mefloquine

• CAS: 53230-10-7
• Catalog Number: ACM53230107
• Category: Inhibitors
• Molecular Weight: 378.32
• Molecular Formula: C₁₇H₁₆F₆N₂O
• Description: Mefloquine (Mefloquin), an orally active and potent quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus and cancer research.
• Synonyms: MEFLOQUINE;MEFLOQUINE INTERMEDIATE;Mefloquin;Metloquine;(11R,2'S)-Mefloquine;(R)-α-[(2S)-2-Piperidyl]-2,8-bis(trifluoromethyl)-4-quinolinemethanol;(11S,2'R)-Mefloquine;(S)-α-[(2R)-2-Piperidyl]-2,8-bis(trifluoromethyl)-4-quinolinemethanol
• IUPAC Name: (S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol
• SMILES: O[C@H]([C@]1([H])NCCCC1)C2=CC(C(F)(F)F)=NC3=C(C(F)(F)F)C=CC=C32
• InChI Key: XEEQGYMUWCZPDN-DOMZBBRYSA-N
• Boiling Point: 415.7ºC at 760mmHg
• Melting Point: 242-244ºC
• Flash Point: 205.2ºC
• Density: 1.383g/cm³
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Exact Mass: 378.11700
• H-Bond Acceptor: 9
• H-Bond Donor: 2
• Shipping: Can be shipped at room temperature, where not in use may vary.