Lucidone

• CAS: 19956-53-7
• Catalog Number: ACM19956537
• Category: Inhibitors
• Molecular Weight: 256.3
• Molecular Formula: C15H12O4
• Description: Lucidone, an anti-inflammatory agent that can be isolated from the fruit of Lindera erythrocarpa Makino. Lucidone inhibits LPS-induced NO and PGE2 production in RAW 264.7 mouse macrophages. Lucidone also decreases TNF-α secretion, iNOS and COX-2 expression. Lucidone prevents NF-κB translocation and inhibits JNK and p38MAPK signals. Lucidone also has inhibitory activity against Dengue virus (DENV) (EC50=25 μM).
• IUPAC Name: 3-hydroxy-4-methoxy-2-[(E)-3-phenylprop-2-enoyl]cyclopenta-2,4-dien-1-one
• Canonical SMILES: COC1=CC(=O)C(=C1O)C(=O)C=CC2=CC=CC=C2
• InChI: InChI=1S/C15H12O4/c1-19-13-9-12(17)14(15(13)18)11(16)8-7-10-5-3-2-4-6-10/h2-9,18H,1H3/b8-7+
• InChI Key: ANPTXNYQLGJVRE-BQYQJAHWSA-N
• Appearance: Yellow powder