CAS
2763260-36-0 Purity
>99.5%
2763260-36-0 Purity
>99.5%
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LSN3160440
CAS
2765539-59-9
Catalog Number
ACM-MG-2765539599
Category
Molecular Glues
Molecular Weight
480.43
Molecular Formula
C27H27Cl2N3O
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Specification
Description
LSN3160440 is an allosteric modulator of GLP-1R, functioning as a protein-protein interaction (PPI) stabilizer or molecular glue. It aids in the binding of inactive GLP-1 (9-36) NH2 to GLP-1R, enhancing receptor activation and potential therapeutic effects.
Synonyms
1-[(1R)-1-(2,6-dichloro-3-methoxyphenyl)ethyl]-6-{2-[(2R)-piperidin-2-yl]phenyl}-1H-benzimidazole
IUPAC Name
1-[(1R)-1-(2,6-dichloro-3-methoxyphenyl)ethyl]-6-[2-[(2R)-piperidin-2-yl]phenyl]benzimidazole
SMILES
C[C@H](C1=C(C=CC(=C1Cl)OC)Cl)N2C=NC3=C2C=C(C=C3)C4=CC=CC=C4[C@H]5CCCCN5
InChI
InChI=1S/C27H27Cl2N3O/c1-17(26-21(28)11-13-25(33-2)27(26)29)32-16-31-23-12-10-18(15-24(23)32)19-7-3-4-8-20(19)22-9-5-6-14-30-22/h3-4,7-8,10-13,15-17,22,30H,5-6,9,14H2,1-2H3/t17-,22-/m1/s1
InChI Key
YFCMSHPEVDOMQA-VGOFRKELSA-N
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