Lenalidomide-d5

• CAS: 1227162-34-6
• Catalog Number: ACM-MG-1227162346
• Category: Molecular Glues
• Molecular Weight: 264.29
• Molecular Formula: C13H8D5N3O3
• Description: Lenalidomide-d5 is deuterium labeled Lenalidomide. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase.
• Synonyms: CC-5013-d5
• IUPAC Name: 3-(7-amino-3-oxo-1H-isoindol-2-yl)-3,4,4,5,5-pentadeuteriopiperidine-2,6-dione
• SMILES: O=C1N(C2([2H])C(NC(C([2H])([2H])C2([2H])[2H])=O)=O)CC3=C(N)C=CC=C31
• InChI: InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)/i4D2,5D2,10D
• InChI Key: GOTYRUGSSMKFNF-QTQWIGFBSA-N
• Appearance: White to off-white solid
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Store at -20 °C