Structure

KX2-361

CAS
897016-26-1
Catalog Number
ACM-MG-897016261
Category
Molecular Glues
Molecular Weight
405.46
Molecular Formula
C24H24FN3O2

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Specification

Description
KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma
Synonyms
KX-02
IUPAC Name
N-[(3-fluorophenyl)methyl]-2-[5-(4-morpholin-4-ylphenyl)pyridin-2-yl]acetamide
SMILES
C(C(NCC1=CC(F)=CC=C1)=O)C=2C=CC(C3=CC=C(C=C3)N4CCOCC4)=CN2
InChI
InChI=1S/C24H24FN3O2/c25-21-3-1-2-18(14-21)16-27-24(29)15-22-7-4-20(17-26-22)19-5-8-23(9-6-19)28-10-12-30-13-11-28/h1-9,14,17H,10-13,15-16H2,(H,27,29)
InChI Key
CMKKPJNMYLOUCE-UHFFFAOYSA-N
Density
1.31 g/cm3
Solubility
DMSO: 8.75 mg/mL (21.58 mM)
Shipping
Shipping with blue ice.
Storage Conditions
Powder: Store at -20 °C for 3 years
In solvent: -80 °C for 1 year

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