Inavolisib

• CAS: 2060571-02-8
• Catalog Number: ACM-MG-2060571028
• Category: Molecular Glues
• Molecular Weight: 407.38
• Molecular Formula: C18H19F2N5O4
• Description: Inavolisib (GDC-0077) is a potent, orally available, and selective PI3Ka inhibitor (IC50=0.038 nM).
• Synonyms: GDC-0077
• IUPAC Name: (2S)-2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide
• SMILES: C[C@H](NC1=CC=C2C3=NC(=CN3CCOC2=C1)N1[C@@H](COC1=O)C(F)F)C(N)=O
• InChI: InChI=1S/C18H19F2N5O4/c1-9(16(21)26)22-10-2-3-11-13(6-10)28-5-4-24-7-14(23-17(11)24)25-12(15(19)20)8-29-18(25)27/h2-3,6-7,9,12,15,22H,4-5,8H2,1H3,(H2,21,26)/t9-,12-/m0/s1
• InChI Key: SGEUNORSOZVTOL-CABZTGNLSA-N
• Solubility: Soluble in DMSO, DMF
• Appearance: White solid
• Shipping: Room temperature
• Storage Conditions: Refrigerated