Structure

IKZF2-degrader 1

CAS
2983840-43-1
Catalog Number
ACM-MG-2983840431
Category
Molecular Glues
Molecular Weight
519.57
Molecular Formula
C27H30FN7O3

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Specification

Description
IKZF2-degrader 1 (Compound 31) is a IKZF2 molecular glue degrader, with an DC50 of 0.5 nM. IKZF2-degrader 1 has minimal CK1α degradation activity relatively (DC50: 210 nM). IKZF2-degrader 1 can be used for research of IKZF2-dependent cancers.
SMILES
CC(C)NC1=NNC2=C(CN3CCCC3)C=C(C4=C(F)C(CN(C5CCC(NC5=O)=O)C6=O)=C6C=C4)N=C21
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Please store the product under the recommended conditions.

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