IKZF1-degrader-1

• CAS: 2915586-02-4
• Catalog Number: ACM-MG-2915586024
• Category: Molecular Glues
• Molecular Weight: 605.63
• Molecular Formula: C35H29F2N5O3
• Description: IKZF1-degrader-1 (Compound 9-B) is a IKZF1 molecular glue degrader with the DC50 value of 0.134 nM. IKZF1-degrader-1 can be used to degrader tumors.
• IUPAC Name: 4-[4-[[4-[[1-[(3S)-2,6-dioxopiperidin-3-yl]-4-fluoro-2-oxobenzo[cd]indol-6-yl]methyl]phenyl]methyl]piperazin-1-yl]-3-fluorobenzonitrile
• SMILES: O=C1N([C@@H]2C(NC(CC2)=O)=O)C3=CC=C(C4=CC(F)=CC1=C43)CC5=CC=C(C=C5)CN6CCN(C7=C(C=C(C=C7)C#N)F)CC6
• InChI: InChI=1S/C35H29F2N5O3/c36-25-17-26-24(6-8-30-33(26)27(18-25)35(45)42(30)31-9-10-32(43)39-34(31)44)15-21-1-3-22(4-2-21)20-40-11-13-41(14-12-40)29-7-5-23(19-38)16-28(29)37/h1-8,16-18,31H,9-15,20H2,(H,39,43,44)/t31-/m0/s1
• InChI Key: HULAZOQCQMEDII-HKBQPEDESA-N
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Please store the product under the recommended conditions.