CAS
--- Purity
---
--- Purity
---
Shopping basket
IBG3
Catalog Number
ACM-MG-00021
Category
Molecular Glues
Molecular Weight
976.22
Molecular Formula
C54H57N9O5S2
If you have any other questions or need other size, please get a quote.
- Product Description
- Case Study
- Custom Reviews
- Custom Q&A
- Synthetic Use
- Related Resources
Specification
Description
IBG3 is a dual-JQ1-containing BET degrader that targets protein degradation via intramolecular bivalent glues. IBG3 is a BRD2 and BRD4 bifunctional degrader with DC50 values of 8.6 pM and 6.7 pM, respectively.
SMILES
O=C(NCC1=CC=C(C2=N[C@@H](CC(OC(C)(C)C)=O)C3=NN=C(C)N3C4=C2C(C)=C(C)S4)C=C1)C5=CC=C(C6=CC=C(C7=N[C@@H](CC(OC(C)(C)C)=O)C8=NN=C(C)N8C9=C7C(C)=C(C)S9)C=C6)C=C5
Appearance
Off-white to light yellow solid
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Store at 4 °C
Please kindly note that our products are for research use only.
Recommended Products
