5-Hydroxythalidomide

• CAS: 64567-60-8
• Catalog Number: ACM-MG-64567608
• Category: Molecular Glues
• Molecular Weight: 274.23
• Molecular Formula: C13H10N2O5
• Description: Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. It induces degradation of SALL4 (ZF2).
• Synonyms: Thalidomide-5-OH
• IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindole-1,3-dione
• SMILES: OC1=CC2=C(C=C1)C(=O)N(C1CCC(=O)NC1=O)C2=O
• InChI: InChI=1S/C13H10N2O5/c16-6-1-2-7-8(5-6)13(20)15(12(7)19)9-3-4-10(17)14-11(9)18/h1-2,5,9,16H,3-4H2,(H,14,17,18)
• InChI Key: LJBQRRQTZUJWRC-UHFFFAOYSA-N
• Solubility: Soluble in DMSO, DMF
• Appearance: White solid
• EC Number: 965-879-3
• Shipping: Room temperature
• Storage Conditions: Refrigerated