HB007

• CAS: 2387821-46-5
• Catalog Number: ACM-MG-2387821465
• Category: Molecular Glues
• Molecular Weight: 344.84
• Molecular Formula: C15H9ClN4S2
• Description: HB007 is a small ubiquitin-related modifier 1 (SUMO1) degrader. HB007 induces ubiquitination and degradation of SUMO1, resulting in reduced tumor growth in vivo. HB007 can be used for the research of brain, breast, colon, and lung cancers.
• Synonyms: 1-(3-Chlorophenyl)-3-(6-cyano-1,3-benzothiazol-2-yl)urea
• IUPAC Name: 1-(3-chlorophenyl)-3-(6-cyano-1,3-benzothiazol-2-yl)urea
• SMILES: ClC1=CC(NC(=S)NC2=NC3=C(S2)C=C(C=C3)C#N)=CC=C1
• InChI: InChI=1S/C15H9ClN4OS/c16-10-2-1-3-11(7-10)18-14(21)20-15-19-12-5-4-9(8-17)6-13(12)22-15/h1-7H,(H2,18,19,20,21)
• InChI Key: URCZUKFRZQNQSQ-UHFFFAOYSA-N
• Solubility: Soluble in DMSO, DMF
• Appearance: White solid
• Shipping: Room temperature
• Storage Conditions: Refrigerated