Gatifloxacin sesquihydrate

• CAS: 180200-66-2
• Catalog Number: ACM180200662
• Category: Inhibitors
• Molecular Weight: 402.42
• Molecular Formula: C₁₉H₂₂FN₃O₄.1.5(H₂O)
• Description: Gatifloxacin sesquihydrate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin sesquihydrate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin sesquihydrate can be used to treat bacterial conjunctivitis in vivo.
• Synonyms: AKOS NCG1-0010;1-CYCLOPROPYL-6-FLUORO-8-METHOXY-7-(3-METHYL-PIPERAZIN-1-YL)-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID;1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-8-METHOXY-7-(3-METHYLPIPERAZIN-1-YL)-4-OXO-3-QUINOLINECARBOXYLIC ACID;1-CYCLOPROPYL-6-FLUORO-1,4-
• Density: 1.386 g/cm³
• Appearance: Almost white to light yellow crystalline powder