Fmoc-Gln(Trt)-OH

• CAS: 132327-80-1
• Catalog Number: ACM132327801
• Category: Amino Acids
• Molecular Weight: 610.7
• Molecular Formula: C39H34N2O5
• Description: High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.; Fmoc-Gln(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Gln. Coupling can be performed by standard procedures. The trityl-protecting group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp.; Literature references; P. Sieber, et al. (1991) Tetrahedron Lett., 32, 739
• Synonyms: Fmoc-Gln(Trt)-OH, N-α-Fmoc-N-γ-trityl-L-glutamine
• InChI: 1S/C39H34N2O5/c42-36(41-39(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29)25-24-35(37(43)44)40-38(45)46-26-34-32-22-12-10-20-30(32)31-21-11-13-23-33(31)34/h1-23,34-35H,24-26H2,(H,40,45)(H,41,42)(H,43,44)/t35-/m0/s1
• InChI Key: WDGICUODAOGOMO-DHUJRADRSA-N
• Melting Point: 110-125℃
• Application: Peptide synthesis.
• Assay: ≥93.0% (acidimetric); ≥98% (TLC); ≥99.0% (HPLC)
• Form: powder
• Functional Group: amide
• MDL Number: MFCD00077056
• Quality Level: 400
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: -10 to -25℃
• Type: Unlabeled Standard Amino Acids, Glutamine (Gln)