Structure

ER degrader 9

CAS
3023359-75-0
Catalog Number
ACM-MG-3023359750
Category
Molecular Glues
Molecular Weight
616.83
Molecular Formula
C40H48N4O2

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Specification

Description
ER degrader 9 (compound 1), a bifunctional molecule, is a potent estrogen receptor (ER) degrader with a DC50 of ≤10 nM in MCF-7 cells. ER degrader 9 can be used for the research of breast cancer.
SMILES
CC(C)(/C=C(C(N1CCN(CC1)CC2CCN(CC2)C3=CC=C(C=C3)[C@H]4[C@H](CCC5=CC(O)=CC=C54)C6=CC=CC=C6)=O)/C#N)C
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.

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