dCeMM4

• CAS: 1281683-44-0
• Catalog Number: ACM-MG-1281683440
• Category: Molecular Glues
• Molecular Weight: 337.42
• Molecular Formula: C14H15N3O3S2
• Description: dCeMM4 (Compound 5) is a glue degrader. dCeMM4 induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex.
• IUPAC Name: 3-(5-methylfuran-2-carbonyl)-N-(5-methyl-1,3-thiazol-2-yl)-1,3-thiazolidine-4-carboxamide
• SMILES: CC1=CC=C(O1)C(N2CSCC2C(/N=C3NC=C(S/3)C)=O)=O
• InChI: InChI=1S/C14H15N3O3S2/c1-8-3-4-11(20-8)13(19)17-7-21-6-10(17)12(18)16-14-15-5-9(2)22-14/h3-5,10H,6-7H2,1-2H3,(H,15,16,18)
• InChI Key: BPWZJVKIVHVVHP-UHFFFAOYSA-N
• Appearance: Light yellow to yellow soild
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Store at 4 °C