CAS
--- Purity
≥95%
--- Purity
≥95%
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Cyclosporin A-d12
Catalog Number
ACM-MG-00016
Category
Molecular Glues
Molecular Weight
1214.69
Molecular Formula
C62H99D12N11O12
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Specification
Description
Cyclosporin A-d12 (Cyclosporine A-d12) is deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 adhesion.
Synonyms
Cyclosporine A-d12; Ciclosporin A-d12; CsA-d12
SMILES
C/C=C/C[C@@H](C)[C@H]([C@]1([H])N(C([C@](C(C)C)(N(C([C@@H](N(C([C@](CC(C)C)(N(C([C@H](NC([C@@H](NC([C@H](CC(C)C)N(C)C([C@@](NC([C@H](CC(C)C)N(C)C(CN(C)C([C@H](CC)NC1=O)=O)=O)=O)(C(C)C)[H])=O)=O)C)=O)C)=O)C)[H])=O)C([2H])([2H])[2H])C([2H])(C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])[2H])=O)C)[H])=O)C)O
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Please store the product under the recommended conditions.
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