CAS
--- Purity
≥95%
--- Purity
≥95%
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Cyclosporin A acetate-d4
Catalog Number
ACM-MG-00015
Category
Molecular Glues
Molecular Weight
1248.67
Molecular Formula
C64H109D4N11O13
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Specification
Description
Cyclosporin A acetate-d4 is a deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 adhesion.
Synonyms
Cyclosporine A acetate-d4; Ciclosporin A acetate-d4; CsA acetate-d4
SMILES
CC(O[C@@H]([C@]1([H])N(C([C@@H](N(C([C@@H](N(C([C@@H](N(C([C@H](NC([C@@H](NC([C@@H](N(C([C@@H](NC([C@@H](N(C(CN(C([C@@H](NC1=O)CC)=O)C)=O)C)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)C)=O)C)=O)C)CC(C)C)=O)C)CC(C)C)=O)C)C(C)C)=O)C)[C@H](C)C/C=C([2H])/C([2H])([2H])[2H])=O
Appearance
White to off-white solid
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Store at -20 °C
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