52693-61-5 Purity
95%
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Specification
dos Santos, Edielen F., et al. Journal of Applied Polymer Science 141.31 (2024): e55736.
Microneedles (MNs) present a promising approach for minimally invasive, painless drug delivery. Stereolithography (SLA) additive manufacturing offers significant potential for fabricating precise MN structures. This case study detailed the development and evaluation of a novel photopolymerizable resin formulation specifically designed for SLA fabrication of biocompatible microneedles. The primary monomer component is Cyclohexanedimethanol Dimethacrylate (CDMM).
Key Findings
· X-ray diffraction (XRD) analysis was performed specifically on the CDMM monomer to elucidate its crystallographic structure. Results demonstrated that CDMM crystallizes in the monoclinic crystal system, corresponding to the P21/c space group.
· The conical microneedles produced, measuring approximately 655 μm in height, underwent comprehensive mechanical and thermal evaluations.
· Optical coherence tomography and histological analyses were utilized to assess the depth of micro-perforations in Parafilm M and pig skin, confirming effective penetration through the stratum corneum and epidermal layers into the superficial dermis (1.5-4 mm thick) without damaging nerve endings.
· Cytocompatibility tests validate the microneedles' biocompatibility. This study underscores the potential of the newly developed biocompatible material for printable drug delivery systems, particularly in creating microneedles and other implantable forms.
The molecular formula of Cyclohexanedimethanol dimethacrylate is C16H24O4.
The synonyms of Cyclohexanedimethanol dimethacrylate include 52892-97-4, 1,4-Cyclohexanedimethyl 1,4-dimethacrylate, 1,4-Cyclohexanediylbis(methylene) bismethacrylate, and Cyclohexane-1,4-dimethanol dimethacrylate.
The molecular weight of Cyclohexanedimethanol dimethacrylate is 280.36 g/mol.
Cyclohexanedimethanol dimethacrylate was created on August 8, 2005.
Cyclohexanedimethanol dimethacrylate was last modified on October 21, 2023.
The IUPAC name of Cyclohexanedimethanol dimethacrylate is [4-(2-methylprop-2-enoyloxymethyl)cyclohexyl]methyl 2-methylprop-2-enoate.
The InChI of Cyclohexanedimethanol dimethacrylate is InChI=1S/C16H24O4/c1-11(2)15(17)19-9-13-5-7-14(8-6-13)10-20-16(18)12(3)4/h13-14H,1,3,5-10H2,2,4H3.
The InChIKey of Cyclohexanedimethanol dimethacrylate is NKIDFMYWMSBSRA-UHFFFAOYSA-N.
The canonical SMILES of Cyclohexanedimethanol dimethacrylate is CC(=C)C(=O)OCC1CCC(CC1)COC(=O)C(=C)C.
The CAS number of Cyclohexanedimethanol dimethacrylate is 52892-97-4.
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