CQ627

• Catalog Number: ACM-MG-00014
• Category: Molecular Glues
• Molecular Weight: 697.64
• Molecular Formula: C36H27F4N7O4
• Description: CQ627 is a molecular glue targeting the degradation of RIOK2. It effectively induces the degradation of RIOK2 in the MOLT4 leukemia cell line via the ubiquitin-proteasome system (UPS) by recruiting the E3 ubiquitin ligase RNF126, with a DC50 value of 410 nM.
• SMILES: FC1=CC=C(C(/C=C/C(N2CCN(C3=C(C(F)(F)F)C=C(N4N=NC5=C4C6=CC(C7=CC=C(OC)N=C7)=CC=C6NC5=O)C=C3)CC2)=O)=O)C=C1
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Please store the product under the recommended conditions.