Chlorhexidine

• Catalog Number: ACM55561
• Product Name: Chlorhexidine
• CAS: 55-56-1
• Category: Main Products
• Synonyms: 1,1’-Hexamethylenebis(5-(p-chlorophenyl)-biguanid;1,6-bis(5-(p-chlorophenyl)biguandino)hexane; 1,6-bis(p-chlorophenyldiguanido)hexane
• IUPAC Name: (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine
• Molecular Weight: 505.45
• Molecular Formula: C22H30Cl2N10
• InChI: InChI=1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)
• InChI Key: GHXZTYHSJHQHIJ-UHFFFAOYSA-N
• Melting Point: 134-136 °C (lit.)
• Density: 1.39 g/cm³
• Solubility: Soluble in water (0.08%) at 20 °C
• Appearance: White powder
• Assay: 0.999
• Complexity: 649
• EC Number: 200-238-7
• Exact Mass: 504.2031964
• Formal Charge: 0
• Hazard Statements: Xi,N
• Heavy Atom Count: 34
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 6
• Isomeric SMILES: C1=CC(=CC=C1N/C(=N/C(=NCCCCCCN=C(/N=C(/NC2=CC=C(C=C2)Cl)\N)N)N)/N)Cl
• MDL Number: MFCD00009673
• Monoisotopic Mass: 504.2031964
• Packaging: 1 kg
• Packing Group: III
• Physical State: Solid
• Rotatable Bond Count: 13
• Safety Description: 26-36/37-60-61
• Stability: Stable. Incompatible with strong oxidizing agents.
• Storage Conditions: Room temperature
• Supplemental Hazard Statements: H315-H319-H334-H335-H410
• Symbol: GHS07,GHS08,GHS09
• Topological Polar Surface Area: 178 Ų
• WGK Germany: 3

Custom Q&A

What is the molecular formula of Chlorhexidine?

The molecular formula of Chlorhexidine is C22H30Cl2N10.

What is the molecular weight of Chlorhexidine?

The molecular weight of Chlorhexidine is 505.4 g/mol.

What is Chlorhexidine used for?

Chlorhexidine is used as a broad-spectrum antimicrobial biguanide. It is used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.

How is Chlorhexidine structured?

Chlorhexidine has a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge. It is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.

What are the synonyms for Chlorhexidine?

The synonyms for Chlorhexidine include Rotersept, Fimeil, and Hexadol.

When was Chlorhexidine created?

Chlorhexidine was created on October 23, 2006.

When was Chlorhexidine last modified?

Chlorhexidine was last modified on October 21, 2023.

What is the physiologic effect of Chlorhexidine?

The physiologic effect of Chlorhexidine is by means of decreased cell wall integrity.

What are some FDA-approved formulations of Chlorhexidine?

The FDA withdrew its approval for the use of chlorhexidine gluconate topical tincture 0.5%. However, other formulations of chlorhexidine continue to be available.

What is the InChIKey of Chlorhexidine?

The InChIKey of Chlorhexidine is GHXZTYHSJHQHIJ-UHFFFAOYSA-N.