Structure

CC-3060

CAS
444288-86-2
Catalog Number
ACM-MG-444288862
Category
Molecular Glues
Molecular Weight
403.39
Molecular Formula
C22H17N3O5

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Specification

Description
CC-3060 is a Cereblon modulator and promotes ZBTB16 degradation by primarily engaging distinct structural degrons on CRBN-ZnF1 zinc finger domains.
IUPAC Name
4-(1-benzofuran-2-ylmethylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
SMILES
O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C1C=CC=C2NCC1=CC2=CC=CC=C2O1
InChI
InChI=1S/C22H17N3O5/c26-18-9-8-16(20(27)24-18)25-21(28)14-5-3-6-15(19(14)22(25)29)23-11-13-10-12-4-1-2-7-17(12)30-13/h1-7,10,16,23H,8-9,11H2,(H,24,26,27)
InChI Key
GRICLJZNEMDVMA-UHFFFAOYSA-N
Solubility
Soluble in DMSO, DMF
Appearance
White solid
Shipping
Room temperature
Storage Conditions
Refrigerated

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