CC-885

• CAS: 1010100-07-8
• Catalog Number: ACM-MG-1010100078
• Category: Molecular Glues
• Molecular Weight: 440.88
• Molecular Formula: C22H21ClN4O4
• Description: CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity. CC-885 is also a known degrader of GSPT1, inhibiting protein translation.
• IUPAC Name: 1-(3-chloro-4-methylphenyl)-3-[[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]methyl]urea
• SMILES: O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4
• InChI: InChI=1S/C22H21ClN4O4/c1-12-2-4-15(9-17(12)23)25-22(31)24-10-13-3-5-16-14(8-13)11-27(21(16)30)18-6-7-19(28)26-20(18)29/h2-5,8-9,18H,6-7,10-11H2,1H3,(H2,24,25,31)(H,26,28,29)
• InChI Key: DOEVCIHTTTYVCC-UHFFFAOYSA-N
• Appearance: White to off-white solid
• EC Number: 991-036-4
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Store at -20 °C