BU-224 HCl

• CAS: 205437-64-5
• Catalog Number: ACM205437645
• Category: Antagonists
• Molecular Weight: 233.70
• Molecular Formula: C12H12ClN3
• Description: BU-224 is a Putative I2 antagonist; and a high affinity ligand for the imidazoline I2 binding site (Ki = 2.1 nM). BU224 reverses cognitive deficits, reduces microgliosis and enhances synaptic connectivity in a mouse model of Alzheimer's disease.
• Synonyms: BU-224 HCl; BU-224; BU 224; BU224
• IUPAC Name: 2-(4,5-Dihydroimidazol-2-yl)quinoline hydrochloride
• Canonical SMILES: [H]Cl.C1(C2=NCCN2)=NC3=CC=CC=C3C=C1
• InChI: InChI=1S/C12H11N3.ClH/c1-2-4-10-9(3-1)5-6-11(15-10)12-13-7-8-14-12;/h1-6H,7-8H2,(H,13,14);1H
• InChI Key: DDFHQXAQWZWRSQ-UHFFFAOYSA-N
• Solubility: To be determined
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 205437-64-5 (HCl); 187173-05-3 (free base)
• Drug Formulation: To be determined
• Elemental Analysis: C, 61.67; H, 5.18; Cl, 15.17; N, 17.98
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).