BRD9 Degrader-2

• CAS: 3033018-68-4
• Catalog Number: ACM-MG-3033018684
• Category: Molecular Glues
• Molecular Weight: 760.87
• Molecular Formula: C40H43F3N6O4S
• Description: BRD9 Degrader-2 (Compound B11) is a BRD9 degrader (DC50 ≤1.25 nM; Dmax≥75%). BRD9 Degrader-2 can be used for research of cancers.
• IUPAC Name: 2-[5-[[4-[[2,6-dimethoxy-4-(1,4,5-trimethyl-6-oxopyridin-3-yl)phenyl]methyl]piperazin-1-yl]methyl]-1-methyl-3,4-dihydro-1H-isoquinoline-2-carbonyl]-3-[4-(trifluoromethyl)-1,3-thiazol-2-yl]prop-2-enenitrile
• SMILES: N#C/C(C(N1CCC2=C(C1C)C=CC=C2CN3CCN(CC3)CC4=C(OC)C=C(C5=CN(C)C(C(C)=C5C)=O)C=C4OC)=O)=C\C6=NC(C(F)(F)F)=CS6
• InChI: InChI=1S/C40H43F3N6O4S/c1-24-25(2)38(50)46(4)21-32(24)28-16-34(52-5)33(35(17-28)53-6)22-48-14-12-47(13-15-48)20-27-8-7-9-30-26(3)49(11-10-31(27)30)39(51)29(19-44)18-37-45-36(23-54-37)40(41,42)43/h7-9,16-18,21,23,26H,10-15,20,22H2,1-6H3
• InChI Key: LGLQCBGPDQBRIS-UHFFFAOYSA-N
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Please store the product under the recommended conditions.