Boc-D-Tyr-OH

• CAS: 70642-86-3
• Catalog Number: ACM70642863
• Category: Amino Acids
• Molecular Weight: 281.3
• Description: Standard building block for introduction of D-tyrosine amino-acid residues by Boc SPPS.
• Synonyms: Boc-D-Tyr-OH, N-α-t.-Boc-D-tyrosine
• InChI: 1S/C14H19NO5/c1-14(2,3)20-13(19)15-11(12(17)18)8-9-4-6-10(16)7-5-9/h4-7,11,16H,8H2,1-3H3,(H,15,19)(H,17,18)/p-1/t11-/m1/s1
• InChI Key: CNBUSIJNWNXLQQ-LLVKDONJSA-M
• Application: Peptide synthesis.
• Assay: ≥98% (TLC)
• Form: powder
• Functional Group: hydroxyl
• MDL Number: MFCD00063030
• Quality Level: 200
• Reaction Suitability: reaction type: Boc solid-phase peptide synthesis
• Storage Temperature: 2-30℃

Synthetic Use

Upstream Synthesis Route 1

• 24424-99-5
• 556-02-5

• 70642-86-3

Reference: [1] Tetrahedron Letters, 2017, vol. 58, # 21, p. 2031 - 2033
[2] Synthesis, 2002, # 13, p. 1867 - 1870
[3] Tetrahedron Letters, 2007, vol. 48, # 26, p. 4509 - 4513
[4] Journal of Medicinal Chemistry, 2011, vol. 54, # 16, p. 5680 - 5693
[5] Chemistry - A European Journal, 2014, vol. 20, # 10, p. 2953 - 2959

Upstream Synthesis Route 2

• 556-02-5

• 70642-86-3

Reference: [1] Patent: US6362165, 2002, B1,

Upstream Synthesis Route 3

• 76757-90-9

• 70642-86-3

Reference: [1] Journal of Organic Chemistry, 2000, vol. 65, # 16, p. 5037 - 5042

Upstream Synthesis Route 4

• 1070-19-5
• 3417-91-2

• 3978-80-1
• 70642-86-3

Reference: [1]Acta Chimica Academiae Scientiarum Hungaricae,1981,vol. 107,p. 7 - 9

Downstream Synthesis Route 1

• 74-96-4
• 70642-86-3

• 76757-92-1

Reference: [1]Journal of Organic Chemistry,1983,vol. 48,p. 4127 - 4129

Downstream Synthesis Route 2

• 64-67-5
• 70642-86-3

• 76757-92-1

Reference: [1]Journal of Medicinal Chemistry,1982,vol. 25,p. 45 - 50

* For details of the synthesis route, please refer to the original source to ensure accuracy.