Amodiaquine-d10

• Catalog Number: ACM1189449704
• Product Name: Amodiaquine-d10
• CAS: 1189449-70-4
• Category: Inhibitors
• Description: Amodiaquine-d10 is the deuterium labeled Amodiaquine. Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect.
• Synonyms: 4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino-d10)methyl]phenol; 4-[(7-Chloro-4-quinolyl)amino]-α-(diethylamino-d10)-o-cresol; Camochin-d10; Camoquin-d10; Camoquinal-d10; Camoquine-d10; Flavoquine-d10; Miaquin-d10; NSC 13453-10; SN-10751-d10
• Molecular Weight: 365.92
• Molecular Formula: C₂₀H₁₂D₁₀ClN₃O
• Canonical SMILES: ClC(C=C1)=CC2=C1C(NC3=CC(CN(C([2H])([2H])C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H])=C(C=C3)O)=CC=N2
• Appearance: Pale Yellow Solid
• Storage: Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
• Shipping: Can be shipped at room temperature, where not in use may vary.