CAS
78213-63-5 Purity
>99 %
78213-63-5 Purity
>99 %
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a-3 Hydrochloride
CAS
78957-85-4
Catalog Number
ACM78957854
Category
Inhibitors
Molecular Weight
321.22
Molecular Formula
C12H14Cl2N2O2S
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Specification
Description
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (Ki=4.3 µM), casein kinase II (Ki=5.1 µM) and myosin light chain kinase (MLCK) (Ki=7.4 µM). A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectively.
Synonyms
A3, Hydrochloride, A3 hydrochloride, IN1547, N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide hydrochloride, N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide, HCl, A-3HYDROCHLORIDE, A1980_SIGMA, SCHEMBL3503907, CHEMBL1255867, CTK7E9088, OR0890T, MolPort-001-756-823, CCG-222331, LP01027, NCGC00094317-01, 3B3-053691, N-(2-Aminoethyl)-5-chloronaphthalene-1-sulphonamide hydrochloride, N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE, HYDROCHLORIDE, 78957-85-4
IUPAC Name
N-(2-aminoethyl)-5-chloronaphthalene-1-sulfonamide;hydrochloride
InChI Key
VWAGIWCLJAQLAL-UHFFFAOYSA-N
Melting Point
173-176ºC
Exact Mass
320.01500
Hazard Statements
Xi: Irritant;
H-Bond Acceptor
4
H-Bond Donor
3
Safety Description
26-36
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