2-Chloro-4-(4-boc-1-piperazinyl)pyrimidine

• CAS: 221050-88-0
• Catalog Number: ACM221050880
• Category: Other Products
• Molecular Formula: C₁₃H₁₉ClN₄O₂
• Synonyms: 1-Boc-4-(2-Chloropyrimidin-4-yl)piperazine;tert-Butyl 4-(2-chloropyrimidin-4-yl)piperazine-1-carboxylate

Synthetic Use

Upstream Synthesis Route 1

• 3934-20-1
• 57260-71-6

• 221050-88-0

Reference: [1] Patent: CN108503645, 2018, A, . Location in patent: Paragraph 0117-0119

Upstream Synthesis Route 2

• 7461-50-9
• 57260-71-6

• 221050-88-0

Reference: [1] Patent: WO2011/95196, 2011, A1, . Location in patent: Page/Page column 114

Upstream Synthesis Route 3

• 3934-20-1
• 57260-71-6

• 221050-88-0
• 479691-42-4

Reference: [1]Patent: US2005/176722,2005,A1 .Location in patent: Page/Page column 20; 22

Downstream Synthesis Route 1

• 1193-21-1
• 221050-88-0

• 203519-88-4

Reference: [1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 4, p. 1468 - 1478

Downstream Synthesis Route 2

• 221050-88-0

• 634468-87-4

Reference: [1]Current Patent Assignee: SANOFI - US2005/176722, 2005, A1
Location in patent: Page/Page column 20

Downstream Synthesis Route 3

• 221050-88-0
• 79538-20-8

• 479690-80-7

Reference: [1]Current Patent Assignee: PFIZER INC - US2003/105106, 2003, A1

* For details of the synthesis route, please refer to the original source to ensure accuracy.