1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt

• CAS: 32588-53-7
• Catalog Number: ACM32588537
• Category: Main Products
• Molecular Weight: 377.26
• Molecular Formula: HOC10H4(NO)(SO3Na)2
• IUPAC Name: 1-NITROSO-2-NAPHTHOL-3,6-DISULFONIC ACID DISODIUM SALT
• Melting Point: 300ºC
• Exact Mass: 376.92500
• Hazard Statements: Xn: Harmful
• Safety Description: 22-24/25

Case Study

Multi-Metal Photometric Detection via 1-Nitroso-2-Naphthol-3,6-Disulfonic Acid Disodium Salt-Immobilized Gelatin Films

Reshetnyak, Elena, Nataliia Ivchenko, et al. Open Chemistry 10.5 (2012): 1617-1623.

The utility of 1-nitroso-2-naphthol-3,6-disulfonic acid disodium salt (NRS) as a chromogenic reagent immobilized in gelatin films for simultaneous photometric detection of Co(II), Ni(II), Cu(II) and Fe(III) in aqueous solutions was demonstrated in this study.
Methodology
NRS was electrostatically immobilized in hardened photographic gelatin films (2.5×3.5 cm) by immersion in 1.5×10^-3 M NRS solution for 20 minutes. The yellow films were air-dried and stored at room temperature. Metal detection occurred when films were immersed in analyte solutions for 20 minutes, producing distinct color changes: red-brown (Co2+), green (Fe3+), yellow-brown (Ni2+/Cu2+).
Mechanism
At pH 2 (gelatin's isoelectric point of pH 4.46±0.04), NRS formed 1:3 complexes with Co(II), Fe(III), and Ni(II) (log β' = 6.7, 8.6, 6.4) and 1:2 complexes with Cu(II) (log β' = 8.0), exhibiting characteristic absorption maxima at 430 nm (Co), 470 nm (Ni), 495 nm (Cu), and 720 nm (Fe) versus 370 nm for uncomplexed NRS.
Performance
The system achieved detection limits of 0.45×10^-5 M (Co2+), 0.50×10^-5 M (Fe3+), 0.67×10^-5 M (Cu2+), and 0.75×10^-5 M (Ni2+), with a combined detection limit of 0.82×10^-5 M for total metals, using differential absorbance measurements against reference films.

High-Performance Ascorbic Acid Sensors via Nitroso-R Doped Polypyrrole Electrodes

Mohadesi, A., et al. Russian Journal of Electrochemistry 46.8 (2010): 904-911.

This case study demonstrated nitroso-R's (1-nitroso-2-naphthol-3,6-disulfonic acid disodium) critical function as an anionic dopant and electrocatalyst in polypyrrole-modified electrodes for sensitive ascorbic acid (AA) detection in pharmaceutical applications.
Nitroso-R Modified Electrode
Nitroso-R was integrated into polypyrrole (PPy) films through potentiostatic electropolymerization (750 mV vs. Ag/AgCl, 25s) using a solution containing 25 mM pyrrole and 10 mM nitroso-R. The resulting NR/PPy/Pt electrode exhibited stable doping, with nitroso-R serving dual roles as charge compensator and electrocatalytic mediator.
Performance
This modified electrode can be used to determine AA in various pharmaceutical preparations. The modified electrode demonstrated the linear AA detection range of 0.12-18.54 mM, detection limit of 0.02 mM, low signal deviation: 1.32% RSD, exceptional stability (only 3% current decrease after 20 continuous cycles), superior catalytic rate constant versus other literature reports, and optimal performance in hydrodynamic amperometric mode.

Custom Q&A

What is the molecular formula of 1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt?

The molecular formula is C10H5NNa2O8S2.

What are the synonyms for 1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt?

The synonyms include Nitroso-R salt, Sodium 3-hydroxy-4-nitrosonaphthalene-2,7-disulfonate, Disodium 1-nitroso-2-naphthol-3,6-disulfonate, and more.

What is the CAS number of 1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt?

The CAS number is 525-05-3.

What is the IUPAC name of 1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt?

The IUPAC name is disodium;3-hydroxy-4-nitrosonaphthalene-2,7-disulfonate.

What is the InChI of 1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt?

The InChI is InChI=1S/C10H7NO8S2.2Na/c12-10-8(21(17,18)19)4-5-3-6(20(14,15)16)1-2-7(5)9(10)11-13;;/h1-4,12H,(H,14,15,16)(H,17,18,19);;/q;2*+1/p-2.

What is the InChIKey of 1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt?

The InChIKey is DMKMTGULLYISBH-UHFFFAOYSA-L.

What is the canonical SMILES of 1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt?

The canonical SMILES is C1=CC2=C(C(=C(C=C2C=C1S(=O)(=O)[O-])S(=O)(=O)[O-])O)N=O.[Na+].[Na+].

What is the molecular weight of 1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt?

The molecular weight is 377.3g/mol.

How many hydrogen bond donor counts are there in 1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt?

There is one hydrogen bond donor count.

How many hydrogen bond acceptor counts are there in 1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt?

There are nine hydrogen bond acceptor counts.