tert-Butyl 4-cyano-4-(2-fluoro-4-methylphenyl)piperidine-1-carboxylate

• Catalog: OFC1150315879
• CAS: 1150315-87-9
• Category: Fluorinated Nitriles
• Purity: 97%
• MDL Number: MFCD24470947

• Molecular Formula: C18H23FN2O2
• Molecular Weight: 318.39
• Molar Refractivity: 90.44

• Bioavailability Score: 0.55
• Egan: 0.0
• Ghose: None
• Lipinski: 0.0
• Muegge: 0.0
• Veber: 0.0
• Consensus LogP: 3.46
• MLogP: 2.96
• SILICOS-IT: 3.74
• WLogP: 3.97
• XLogP3: 3.27
• iLogP: 3.35
• BBB Permeant: Yes
• CYP1A2 Inhibitor: No
• CYP2C19 Inhibitor: No
• CYP2C9 Inhibitor: Yes
• CYP2D6 Inhibitor: Yes
• CYP3A4 Inhibitor: No
• GI Absorption: High
• LogKp: -5.92 cm/s
• P-gp Substrate: No
• Fraction Csp3: 0.56

• GHS Pictogram: GHS07
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P305+P351+P338