SR-0987

Description: SR0987 is a RORγt agonist with an EC50 of 800 nM. SR0987 increases IL17 expression while repressing the expression of PD-1.

• Catalog: OFC303126978
• CAS: 303126-97-8
• Category: Fluorinated APIs
• Synonyms: 2-Chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide
• Purity: >98%

• IUPAC Name: 2-chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide
• InChI: InChI=1S/C16H10ClF6NO2/c17-12-4-2-1-3-11(12)13(25)24-10-7-5-9(6-8-10)14(26,15(18,19)20)16(21,22)23/h1-8,26H,(H,24,25)
• InChI Key: IZVBONMVWLTLNT-UHFFFAOYSA-N
• Isomeric SMILES: C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O)Cl

• Molecular Formula: C16H10ClF6NO2
• Molecular Weight: 397.7
• Appearance: White to off-white solid powder

• XLogP3-AA: 4.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 397.0304252 g/mol
• Monoisotopic Mass: 397.0304252 g/mol
• Topological Polar Surface Area: 49.3Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 488